Both men came from Savanakhet Province which borders Vietnam.
They were found carrying the tablets labeled WY, which is the logo for a kind of drug mixed from methamphetamine and caffeine.
Vietnam has some of the world’s toughest drug laws. Those convicted of possessing or smuggling more than 600 grams of heroin or more than 2.5 kilograms of methamphetamine face the death penalty.
The production or sale of 100 grams of heroin or 300 grams of other illegal narcotics is also punishable by death.
Yet drug trafficking activities across the Laos border remains regular.
The Saturday bust came just three days after two Lao men were arrested for trafficking 35 kilograms of opium into Vietnam.